A female client with a history of peptic ulcer disease receives a prescription for misoprostol. Which information provided by the client indicates to the nurse a need for further teaching?

Misoprostol should not be used during pregnancy as it can cause harm to the fetus. Women of childbearing potential should use effective contraception while taking misoprostol. If there is a chance of conception, the healthcare provider should be contacted immediately. A negative pregnancy test is required before starting therapy with misoprostol .