A female client with a history of peptic ulcer disease receives a prescription for misoprostol. Which information provided by the client indicates to the nurse a need for further teaching?

A. Ensure a negative pregnancy test result 2 weeks before therapy: Misoprostol is contraindicated during pregnancy because it can cause uterine contractions and miscarriage. Confirming a negative pregnancy test before starting treatment is essential. B. Begin therapy 1 week before the next normal menstrual cycle: Misoprostol should not be scheduled based on the menstrual cycle. Instead, therapy is initiated after confirming the client is not pregnant and with appropriate contraceptive measures in place. C. Use condoms and a backup method of birth control to prevent pregnancy: Misoprostol poses significant teratogenic and abortifacient risks, reliable contraception with dual methods is strongly recommended throughout therapy. This is appropriate and safe guidance. D. Call the healthcare provider immediately if there is a chance of conception: Prompt notification allows immediate discontinuation of the drug to reduce harm to a potential pregnancy. This is an important precaution to follow during misoprostol therapy.