A heparin infusion is prescribed for a client who weighs 220 pounds. After administering a bolus dose of 80 units/kg, the nurse calculates the infusion rate for the heparin solution at 18 units/kg/hour. The available solution is "Heparin Sodium 25,000 Units in 5% Dextrose Injection 250 mL". The nurse should program the infusion pump to deliver how many mL/hour? (Enter numeric value only. If rounding is required, round to the nearest whole number.)

Calculation: Convert the client's weight from pounds (lb) to kilograms (kg). The client's weight is 220 lb. Client weight (kg) = 220 lb/2.2 lb/kg = 100 kg. Calculate the total heparin dose to be administered per hour (units/hr). The ordered rate is 18 units/kg/hour. Total dose rate (units/hr) = 18 units/kg/hour×100 kg = 1800 units/hr. Determine the concentration of the available solution (units/mL). Available solution is 25,000 units in 250 mL. Concentration (units/mL) = 25,000 units/250 mL = 100 units/mL. Calculate the infusion rate in milliliters per hour (mL/hr). Infusion rate (mL/hr) = Total dose rate (units/hr)/Concentration (units/mL) = 1800 units/hr/100 units/mL = 18 mL/hr.