Pharmacology Chicago State University Proctored Exam
Calculation
A hepatitis B immune globulin contains 312 IU/mL. If the dose is 0.06 mL/kg for certain at-risk persons, (1) is the dose in units for a 154-lb person. Round answer to the nearest tenth. Do not include units.
ml
Explanation & Rationale
Step 1 is to convert the weight from pounds (lbs) to kilograms (kg) Weight in kg = 154 ÷ 2.2 154 ÷ 2.2 = 70 Result at this step = 70 kg Step 2 is to calculate the total volume (mL) to be administered Volume = Weight in kg × Dose (mL/kg) 70 × 0.06 = 4.2 Result at this step = 4.2 mL Step 3 is to calculate the dose in units Total Units = Total mL × Concentration (IU/mL) 4.2 × 312 = 1310.4 Result at this step = 1310.4 Step 4 is to round to the nearest tenth 1310.4 = 1310.4 Answer: 1310.4
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