A hospitalized client diagnosed with schizophrenia is receiving antipsychotic medications. While assessing the client, a nurse identifies signs and symptoms of a dystonic reaction. Which medication would the nurse expect to administer?
Explanation & Rationale
Choice A reason: Aripiprazole, an antipsychotic, may cause dystonic reactions via partial dopamine agonism. It is not used to treat dystonia, as it could worsen extrapyramidal symptoms by altering basal ganglia dopamine signaling, making it inappropriate for acute dystonic reaction management. Choice B reason: Risperidone, an antipsychotic, can cause dystonic reactions due to dopamine D2 receptor blockade in the basal ganglia. Administering it would exacerbate extrapyramidal symptoms, not relieve them, making it unsuitable for treating acute dystonic reactions. Choice C reason: Diphenhydramine, an antihistamine with anticholinergic properties, relieves dystonic reactions by counteracting dopamine blockade-induced basal ganglia dysfunction. It restores cholinergic-dopaminergic balance, reducing muscle spasms and rigidity, making it the standard treatment for antipsychotic-induced acute dystonic reactions. Choice D reason: Propranolol, a beta-blocker, treats tremors or hypertension but not dystonic reactions, which stem from dopamine-cholinergic imbalance in the basal ganglia. It lacks anticholinergic effects needed to reverse dystonia, making it ineffective for this antipsychotic-related side effect.