A major cause of death in children with Stevens-Johnson Syndrome is ___________

A. Sepsis: Stevens-Johnson Syndrome causes widespread skin and mucosal blistering, leading to extensive loss of the protective barrier. This makes children highly vulnerable to secondary infections, and sepsis is the leading cause of mortality. B. Pulmonary embolism: Although immobility and severe illness can increase clot risk, pulmonary embolism is not a primary cause of death in SJS. Infection and sepsis remain the more immediate threats. C. Hyperglycemia: Hyperglycemia may occur due to stress response or corticosteroid therapy, but it is not a major contributor to mortality in SJS. It requires management but is not life-threatening compared to sepsis. D. Hypertension: Blood pressure instability can occur with severe illness, but hypertension is not a direct complication of SJS. Hypotension from sepsis and fluid loss is far more concerning.