A new client presents for surgery. Which finding during the patient assessment would cause the nurse to question the use of propofol?
Explanation & Rationale
A. Family history of malignant hyperthermia: Malignant hyperthermia is a life-threatening hypermetabolic reaction triggered by volatile inhaled anesthetics and depolarizing neuromuscular blockers such as succinylcholine. Propofol is an intravenous anesthetic and is not a known trigger of malignant hyperthermia. B. An egg or soy allergy: Propofol is formulated in a lipid emulsion that contains soybean oil and egg lecithin. Clients with hypersensitivity to egg or soy components may be at increased risk for an allergic reaction when receiving this medication. Because propofol is administered intravenously and acts rapidly, an allergic response could occur quickly and require immediate intervention. C. Post-operative nausea and vomiting at last surgery: Propofol is actually associated with antiemetic properties and has a lower incidence of postoperative nausea and vomiting compared with many inhaled anesthetics. A history of nausea and vomiting after prior anesthesia would not contraindicate its use and may make it a preferred option. D. History of muscular dystrophy: Muscular dystrophy increases the risk of complications with certain neuromuscular blocking agents and inhaled anesthetics, particularly related to rhabdomyolysis or hyperkalemia. Propofol does not directly exacerbate the underlying muscle pathology. Muscular dystrophy alone doesn’t contraindicate propofol administration.