A newborn with transposition of the great arteries, a life threatening cardiac defect, is being admitted to the unit. The nurse should anticipate an order to administer

Rationale: A. Digoxin: Digoxin is used to improve cardiac contractility in heart failure but does not address the underlying anatomical defect in transposition of the great arteries (TGA). It is not the first-line treatment to maintain oxygenation in TGA. B. Prostaglandin E: Prostaglandin E is administered to keep the ductus arteriosus open, allowing mixing of oxygenated and deoxygenated blood, which is critical for survival in newborns with TGA before corrective surgery. C. Furosemide: Furosemide is a diuretic used to manage fluid overload and heart failure symptoms, but it does not address the fundamental need to maintain ductal patency in TGA. D. Indomethacin: Indomethacin is used to close a patent ductus arteriosus, which would be harmful in TGA where keeping the ductus arteriosus open is necessary for adequate oxygenation.