A nurse at an ophthalmology clinic is providing teaching to a client who has open-angle glaucoma and a new treatment regimen of timolol and pilocarpine eye drops. Which of the following instructions should the nurse provide?

Choice A reason: Contact lenses should be removed before administering eye drops, especially with medications like timolol, which can be absorbed by the lens and reduce efficacy or cause irritation. Choice B reason: Administering the medications 5 minutes apart prevents one medication from diluting or washing out the other, ensuring optimal absorption and therapeutic effect. Choice C reason: The tip of the dropper should never touch the eye or any surface to prevent contamination and infection. Choice D reason: Pressure should be applied to the nasolacrimal duct (inner canthus), not the conjunctival sac, for about 1–2 minutes to reduce systemic absorption, especially for beta-blockers like timolol.