A nurse in a provider's office is caring for a client. Exhibits Select the 3 findings from the client's medical record that increase their risk for peptic ulcer disease (PUD).

Rationale: A. Family history increases risk for heart disease and arthritis but is not a direct risk factor for peptic ulcer disease. B. Smoking increases gastric acid secretion, reduces mucosal healing, and significantly raises PUD risk. C. Alcohol use is denied by the client and therefore is not a contributing factor in this case. D. Adalimumab use (an immunosuppressant for rheumatoid arthritis/psoriasis) does not directly increase PUD risk. E. NSAIDs inhibit prostaglandin synthesis, reducing the gastric mucosal barrier and predisposing to ulcer formation. F. H. pylori infection is a primary cause of peptic ulcers due to its damaging effect on gastric mucosa.