A nurse in a provider's office is collecting data from a client.Which of the following findings should the nurse identify as a risk factor for depression? (Select all that apply.)

Choice A rationaleBeing married is generally considered a protective factor against depression due to increased social support and companionship. Research often indicates that individuals in stable marital relationships tend to have lower rates of depression compared to unmarried individuals.Choice B rationaleChronic illness is a significant risk factor for depression. The ongoing physical discomfort, limitations in daily activities, and psychological burden associated with chronic conditions can increase vulnerability to mood disorders. The physiological and emotional impact of managing a long-term illness contributes to this increased risk.Choice C rationaleAlcohol use disorder is strongly associated with an increased risk of depression. Alcohol is a central nervous system depressant that can disrupt neurotransmitter balance in the brain, leading to or exacerbating depressive symptoms. Furthermore, the social and personal consequences of alcohol abuse can contribute to feelings of isolation and despair.Choice D rationaleEarly childhood trauma is a well-established risk factor for developing depression later in life. Adverse experiences during childhood can have long-lasting effects on brain development, stress response systems, and emotional regulation, increasing susceptibility to mental health disorders, including depression.Choice E rationaleMiddle-class economic status is not typically identified as a specific risk factor for depression. While socioeconomic factors can influence mental health, depression can affect individuals across all economic strata. Poverty and financial instability are more commonly associated with increased risk.