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    RN Comprehensive Predictor 2026 Proctored Exam

    A nurse in an emergency department is caring for a client who has morphine toxicity. Which of the following medications should the nurse anticipate administering to the client?

    Explanation & Rationale

    Rationale: A. Disulfiram is used in alcohol use disorder to deter alcohol intake by causing unpleasant effects when alcohol is consumed. It has no role in treating opioid (morphine) toxicity. B. Activated charcoal may be used in certain oral poisonings if given shortly after ingestion, but it is not the primary treatment for opioid toxicity. Additionally, in opioid overdose with respiratory depression, airway and breathing support plus an antidote are priorities over decontamination measures. C. Flumazenil is a benzodiazepine antagonist used to reverse benzodiazepine overdose. It does not reverse opioid effects and is not effective for morphine toxicity. D. Naloxone is an opioid antagonist that rapidly reverses the effects of opioids such as morphine. It competes with opioids at receptor sites, reversing respiratory depression, sedation, and hypotension associated with opioid toxicity. It is the first-line antidote in suspected opioid overdose and should be administered promptly.

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