A nurse in the emergency department is preparing to administer naloxone 0.4 mg IV bolus to client who has opioid-induced respiratory depression. Available is naloxone injection 0.2 mg/mL. How many mL should the nurse administer per dose? (Round the answer to the nearest whole number. Use a leading zero if t applies. Do not use a trailing zero.)

Given: Desired dose: Naloxone 0.4 mg IV bolus Available concentration: Naloxone injection 0.2 mg/mL To find: Volume to administer per dose (in mL) Step 1: Set up the proportion We can use the following proportion to solve the problem: (Desired dose) / (Available concentration) = Volume to administer Step 2: Substitute the values Plugging in the given values, we get: (0.4 mg) / (0.2 mg/mL) = Volume to administer Step 3: Simplify To simplify, we can invert the denominator and multiply: (0.4 mg) x (1 mL / 0.2 mg) = Volume to administer The "mg" units cancel out, leaving us with: (0.4 x 1 mL) / 0.2 = Volume to administer Step 4: Calculate Performing the multiplication and division, we get: 0.4 mL / 0.2 = Volume to administer 2 mL = Volume to administer