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    Ati nsg 1540 pharmacology proctored exam

    A nurse is administering a monoamine oxidase inhibitor (MAOIS) to a client. Which of the following nursing actions is most important to ensure safe medication administration?

    Explanation & Rationale

    A. Monitoring the client's blood pressure regularly: Blood pressure monitoring is important because MAOIs can precipitate hypertensive crises. However, prevention is more critical than detection after the fact. Relying solely on monitoring does not eliminate the underlying trigger for severe hypertension associated with dietary interactions. B. Educating the client on the importance of avoiding foods high in tyramine: MAOIs inhibit monoamine oxidase, the enzyme responsible for breaking down tyramine in the gastrointestinal tract. Accumulation of tyramine leads to excessive norepinephrine release, causing severe vasoconstriction and potentially life-threatening hypertensive crisis. Avoiding aged cheeses, cured meats, fermented products, and certain alcoholic beverages is essential for safety. C. Administering the medication with a full glass of milk: There is no pharmacologic requirement to administer MAOIs with milk. Food does not significantly alter the drug’s mechanism of action related to monoamine oxidase inhibition. D. Assessing the client's fasting blood sugar levels before administration: MAOIs are primarily used for treatment-resistant depression and certain anxiety disorders. They do not directly alter glucose metabolism in a predictable manner that would require routine fasting glucose assessment prior to administration.

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