A nurse is administering pancrelipase to a child who has cystic fibrosis. Which of the following outcomes should the nurse expect as a therapeutic effect of the treatment?

Choice A Reason: Improved respiratory function is incorrect. Pancrelipase primarily helps with the digestion and absorption of fats and fat-soluble vitamins. It does not directly impact respiratory function. Respiratory improvement in cystic fibrosis typically involves treatments such as airway clearance techniques, bronchodilators, and antibiotics to manage lung infections. Choice B Reason: Reduced fat in the stools is correct. Pancrelipase is an enzyme replacement therapy used to treat individuals with cystic fibrosis, a condition that affects the pancreas's ability to produce digestive enzymes. Cystic fibrosis leads to the malabsorption of nutrients, especially fats. Pancrelipase supplements these digestive enzymes and helps the child digest and absorb fat properly. As a result, one of the expected therapeutic effects of pancrelipase is a reduction in fat in the stools, as the enzymes aid in the digestion of dietary fats, leading to improved absorption of nutrients. This, in turn, can help address malnutrition and promote overall health in individuals with cystic fibrosis. Choice C Reason: Improved absorption of vitamins B and C is incorrect. While pancrelipase can help with the absorption of fat-soluble vitamins (A, D, E, and K), it does not directly affect the absorption of vitamins B and C, which are water-soluble vitamins. Cystic fibrosis primarily affects the absorption of fat-soluble vitamins due to impaired fat digestion. Choice D Reason: Decreased sodium excretion is incorrect. Cystic fibrosis is associated with excessive loss of salt (sodium chloride) in sweat. Pancrelipase does not directly affect sodium excretion. Treatment for managing sodium loss typically involves salt supplementation and ensuring proper hydration.