A nurse is administering subcutaneous injections of medication to a client who requires frequent dosing. Which action best demonstrates an understanding of how to prevent muscle atrophy at injection sites?

A. Rotate injection sites is correct because frequent subcutaneous injections in the same site can cause tissue damage, lipodystrophy, and muscle atrophy. Rotating sites allows tissues to recover between injections, reduces discomfort, and improves medication absorption, especially for medications like insulin or heparin. B. Rotate injection sites only if the client asks you to is incorrect because site rotation is a standard nursing practice, not optional. Waiting for the client’s request ignores professional guidelines for safe injection techniques and can lead to tissue damage over time. C. Avoid rotating sites if the current site appears healthy and pain-free to prevent unnecessary tissue trauma is incorrect because even healthy-appearing tissue can develop atrophy or lipohypertrophy with repeated injections. Regular rotation prevents long-term complications. D. Use the same injection site consistently is incorrect because repeated injections in one location increase the risk of scarring, tissue hardening, and impaired absorption. Consistent use of the same site demonstrates poor injection technique.