A nurse is assessing a child who is in sickle cell crisis. Which of the following findings should the nurse expect?

A. Constipation is not a typical manifestation of a sickle cell crisis. B. High fever may occur if an infection is present, but it is not a hallmark symptom of a sickle cell crisis. C. Bradycardia is not expected during a sickle cell crisis; if anything, tachycardia may be seen due to pain or anemia. D. Pain is the most common and significant symptom of a sickle cell crisis, caused by the obstruction of blood flow by sickled red blood cells, leading to ischemia and severe pain. This requires immediate attention and pain management.