A nurse is assessing a client who has a brain tumor and is receiving palliative care. Which of the following findings indicates the nurse should administer pain medication?

A. Cheyne-Stokes respirations: This is a common sign of approaching death but not necessarily an indication for pain medication. B. Constricted pupils: This may indicate opioid use or neurological changes, not pain. C. Mottled skin: Mottling occurs as circulation declines near the end of life, not specifically due to pain. D. Restlessness: In palliative care, restlessness is often a sign of pain or discomfort, even if the client cannot verbalize pain. The nurse should administer prescribed pain medication to ensure comfort.