A nurse is assessing a client who has muscarinic agonist poisoning. Following administration of atropine, which of the following findings should indicate to the nurse that the treatment has been effective?
Explanation & Rationale
B. Muscarinic agonists can cause bradycardia (slow heart rate) due to increased vagal tone. Atropine, as a muscarinic antagonist, increases heart rate by blocking the vagal effects on the heart. A heart rate of 90/min suggests normalization of heart rate, indicating that atropine has been effective in reversing bradycardia.A. Muscarinic agonists can cause excessive gastrointestinal motility and increased bowel sounds. Atropine, by blocking muscarinic receptors, reduces gastrointestinal motility and can lead to decreased bowel sounds. Therefore, hyperactive bowel sounds would suggest ongoing muscarinic stimulation and inadequate response to atropine.C. Muscarinic agonists can cause hypotension (low blood pressure) due to vasodilation and decreased cardiac output. Atropine can cause mild to moderate increases in blood pressure by blocking vasodilation and increasing sympathetic tone. A blood pressure of 90/50 mm Hg suggests persistent hypotension and inadequate response to atropine.D Muscarinic agonists can cause excessive salivation and secretions. Atropine reduces salivation and secretions by blocking muscarinic receptors. Therefore, increased salivation would indicate ongoing muscarinic stimulation and insufficient response to atropine.