A nurse is assessing a client who is receiving gemfibrozil.The nurse should identify which of the following findings as an adverse effect of this medication?
Explanation & Rationale
Choice A rationaleGemfibrozil does not typically cause dependent edema. It primarily acts to lower triglycerides by inhibiting peripheral lipolysis and decreasing hepatic triglyceride production. Edema is not a common adverse effect.Choice B rationaleMuscle tenderness is a known adverse effect of gemfibrozil, as it can cause myopathy or rhabdomyolysis. Patients should report any unexplained muscle pain, tenderness, or weakness, especially if accompanied by malaise or fever.Choice C rationaleTremors are not typically associated with gemfibrozil use. Gemfibrozil's primary adverse effects are gastrointestinal disturbances and musculoskeletal pain, rather than neurological symptoms like tremors.Choice D rationaleHyperkalemia is not a common adverse effect of gemfibrozil. The medication's mechanism of action and common side effects do not include alterations in potassium levels.