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    Ati rn vati comprehensive predictor proctored exam

    A nurse is assessing laboratory values on a client who has taken an overdose of acetaminophen. The nurse should expect which of the following laboratory values indicative of organ damage from the overdose?

    Explanation & Rationale

    A. Alanine aminotransferase (ALT): ALT is an enzyme found primarily in the liver, and elevated levels indicate hepatocellular injury. Acetaminophen overdose can cause severe liver toxicity, so a rise in ALT reflects liver damage and is a key laboratory marker to monitor in this situation. B. Thyroxine (T4): Thyroxine is a thyroid hormone and is unrelated to liver injury or acetaminophen toxicity. Changes in T4 levels do not provide information about organ damage resulting from an overdose. C. Serum amylase: Serum amylase is an enzyme associated with pancreatic function. While elevated amylase indicates pancreatitis, it is not typically affected by acetaminophen overdose and does not reflect hepatotoxicity. D. Creatinine kinase (CK): CK is an enzyme released from muscle tissue during injury or breakdown. While important in assessing muscle damage or rhabdomyolysis, it does not indicate liver damage from acetaminophen toxicity.

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