A nurse is assisting in the education of a group of clients about the contraindications of warfarin therapy. Which of the following statements is appropriate to include in the instructions?

A. Warfarin is teratogenic and can cause fetal malformations or miscarriage; it is contraindicated in pregnancy, especially during the first trimester. B. Diabetes mellitus type 1 is not a contraindication to warfarin; clients with diabetes may take warfarin if indicated, with appropriate monitoring. C. Hypertension is not an absolute contraindication; however, clients with uncontrolled hypertension may have an increased risk of bleeding while on warfarin. D. Rheumatoid arthritis is not a contraindication; warfarin can be used if needed, though drug interactions with other medications for arthritis should be monitored.