A nurse is caring for a 12-year-old client diagnosed with systemic lupus erythematous (SLE). The nurse should recognize which of the following as a common manifestation of SLE?

A. Presence of proteinuria and elevated blood urea nitrogen (BUN) levels: Renal involvement is common in pediatric SLE, often manifesting as lupus nephritis. Proteinuria and elevated BUN indicate impaired kidney function, which is a frequent and serious complication of the disease. B. Increased energy: Children with SLE more commonly experience fatigue and malaise due to systemic inflammation, rather than increased energy levels. C. Weight gain: While weight changes may occur secondary to corticosteroid therapy, spontaneous weight gain is not a typical manifestation of SLE itself. D. Mania: Neuropsychiatric symptoms in SLE can occur, but mania is uncommon in pediatric clients. Cognitive impairment, headaches, or mood changes are more typical neurological manifestations.