A nurse is caring for a 5-year-old child who has nephrotic syndrome. Which of the following findings should indicate to the nurse that treatment has been effective?

A. Temperature 37.2° C (99° F): A normal or slightly elevated temperature does not directly indicate improvement in nephrotic syndrome. While monitoring for infection is important due to immunosuppression risk, temperature alone is not a measure of treatment effectiveness. B. Urine output 256 mL over 8 hr: Increased or adequate urine output indicates that the kidneys are responding to treatment and that edema and fluid retention are improving. Monitoring urine output is a primary indicator of therapeutic effectiveness in managing nephrotic syndrome. C. Odorless urine: Urine odor is not a reliable indicator of nephrotic syndrome resolution. Proteinuria and edema reduction are more relevant markers of effective treatment than changes in urine smell. D. No report of pain with voiding: Absence of dysuria is important for assessing urinary tract comfort but does not reflect resolution of nephrotic syndrome, which primarily involves proteinuria, hypoalbuminemia, and edema.