A nurse is caring for a 54-year-old male client who has been admitted to the hospital for peptic ulcer disease. The client will begin a long-term regimen of omeprazole (Prilosec). The nurse understands that the patient will be at high risk for developing which of the following complications? (Select All That Apply.)

A. Long-term use of omeprazole is associated with an increased risk of osteoporosis and fractures due to decreased calcium absorption caused by reduced stomach acid. This complication is significant in older adults, particularly with prolonged therapy. B. Torsades de Pointes is not a common complication of omeprazole. QT prolongation is more often linked to medications like ondansetron or antiarrhythmics. C. Nausea is not a typical complication of omeprazole; rather, it is a symptom the drug may help alleviate as part of managing gastrointestinal conditions. D. Rebound acid hypersecretion can occur after discontinuation of omeprazole. The body may produce an excessive amount of acid to compensate for the previous suppression, leading to worsening symptoms if the medication is abruptly stopped.