A nurse is caring for a client recently diagnosed with panic disorder. The provider has prescribed pharmacologic treatment. Which of the following medications are commonly used in the treatment of panic disorder? (Select all that apply.)

Choice A reason: Propranolol is a beta-blocker primarily used for performance-related anxiety and physical symptoms like tremors or palpitations. It is not considered first-line or standard treatment for panic disorder. Choice B reason: Clonidine is an alpha-2 adrenergic agonist used more often for hypertension, withdrawal syndromes, and sometimes ADHD. It is not a recommended pharmacologic option for panic disorder. Choice C reason: Alprazolam, a benzodiazepine, is effective for acute management of panic attacks by rapidly reducing anxiety. However, it is generally used short-term due to risks of tolerance, dependence, and withdrawal. Choice D reason: Buspirone is an anxiolytic used mainly for generalized anxiety disorder. It lacks efficacy in panic disorder and is not typically prescribed for it. Choice E reason: Clonazepam, another benzodiazepine, is often used to manage panic disorder due to its longer half-life compared to alprazolam, making it effective in reducing frequency and severity of panic attacks.