A nurse is caring for a client that will receive a diuretic for fluid overload.Which of the following diuretics act on the loop of Henle?

Choice A rationaleSpironolactone is a potassium-sparing diuretic that acts on the collecting ducts and late distal tubules but not on the loop of Henle.Choice B rationaleHydrochlorothiazide is a thiazide diuretic that works on the distal convoluted tubule, not the loop of Henle.Choice C rationaleFurosemide is a loop diuretic that acts on the ascending limb of the loop of Henle to inhibit sodium and chloride reabsorption, leading to increased urine output.Choice D rationaleMannitol is an osmotic diuretic that primarily acts on the proximal tubule and the descending limb of the loop of Henle.