A nurse is caring for a client who has a new prescription for a nitroglycerin transdermal patch. Which of the following actions should the nurse take?

A. Nitroglycerin patches should not be removed for routine activities like bathing unless specifically instructed. B. Nitroglycerin is used to treat hypertension, not induce it. Monitoring for hypertension after applying the patch is unnecessary. C. To prevent skin irritation and tolerance to the medication, it is important to rotate the application sites when using a transdermal patch. This allows the skin to recover and helps maintain the effectiveness of the medication. D. Nitroglycerin patches are typically worn continuously for 12 to 14 hours and then removed for a 10- to 12-hour nitrate-free interval to prevent tolerance to the medication.