A nurse is caring for a client who has a new prescription for spironolactone. Which of the following client findings should the nurse identify as a contraindication to the administration of spironolactone? Select the 3 findings the nurse should identify as a contraindication.

A. Potassium: Spironolactone is a potassium-sparing diuretic. The client’s potassium level of 5.2 mEq/L is above normal, increasing the risk of hyperkalemia. Administering spironolactone in this context is contraindicated until potassium is corrected. B. BUN: Although the BUN is elevated, indicating possible dehydration or renal impairment, it is not an absolute contraindication. Careful monitoring and dose adjustment may be necessary, but it does not automatically preclude spironolactone use. C. Allergy: The client has a sulfonamide allergy. Spironolactone contains a sulfonamide group, which can trigger hypersensitivity reactions. This allergy is a clear contraindication to administering the medication. D. Respiratory rate: The respiratory rate is within a reasonable range and does not affect the safety or efficacy of spironolactone. It is not a contraindication. E. Creatinine: The elevated creatinine (1.7 mg/dL) indicates impaired renal function. Spironolactone can worsen hyperkalemia and fluid retention in clients with kidney dysfunction, making significant renal impairment a contraindication for its use.