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    ATI RN Pharmacology 2023 IV proctored exam

    A nurse is caring for a client who has a prescription for epoetin alfa. Which of the following routes should the nurse plan to use for administration?

    Explanation & Rationale

    B. Epoetin alfa is often administered subcutaneously to provide a slow and sustained release of the medication into the bloodstream. Subcutaneous administration allows for easy access to fatty tissue beneath the skin and provides a suitable absorption rate for the medication.A. Epoetin alfa is a protein-based medication that would be broken down by digestive enzymes in the gastrointestinal tract, rendering it ineffective if taken orally. Therefore, oral administration is not suitable for epoetin alfa.C. Epoetin alfa molecules are too large to pass through the skin barrier effectively. Transdermal delivery systems are typically used for medications that are small, lipid-soluble, and can penetrate the skin's layers to enter the bloodstream.D. Epoetin alfa is not formulated for absorption through nasal mucosa. Intranasal administration is generally reserved for medications that can be absorbed through the nasal membranes, such as certain hormones or medications for nasal conditions.

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