A nurse is caring for a client who has a stool culture that is positive for Clostridioides difficile. Which of the following infection control precautions should the nurse take?

Choice A reason: Removing gloves before leaving the client’s room is incorrect because gloves should be removed inside the room, followed by proper hand hygiene. This prevents contamination of the environment outside the room. Choice B reason: Placing the client in a negative pressure room is used for airborne infections such as tuberculosis, not for C. difficile. C. difficile requires contact precautions, not airborne isolation. Choice C reason: Using an alcohol-based hand rub is ineffective against C. difficile spores. Handwashing with soap and water is required to physically remove spores from the hands. Choice D reason: Wearing a face shield prior to entering the room is correct because C. difficile can spread via contact with contaminated surfaces and body fluids. A face shield protects against splashes during care, and combined with gloves and gowns, it ensures proper contact precautions.