A nurse is caring for a client who has a systemic fungal infection and is receiving IV amphotericin B deoxycholate.During previous infusions, the client developed a fever and chills.Which of the following actions should the nurse take?

Choice A rationaleApplying a warming blanket prior to administration addresses chills but does not prevent fever or other infusion-related reactions to amphotericin B.Choice B rationaleInfusing the medication over 1 hr does not reduce the risk of fever and chills, which are common infusion-related reactions to amphotericin B.Choice C rationaleAdministering diphenhydramine prior to administration can help prevent fever and chills by blocking histamine release, a common response to amphotericin B infusion.Choice D rationaleMonitoring vital signs once per hour following administration does not prevent fever and chills; it only helps in early detection of adverse reactions to amphotericin B. .