A nurse is caring for a client who has diabetes insipidus and is receiving desmopressin by intermittent IV bolus. Which of the following manifestations should the nurse identify as an indication of a therapeutic response to the medication?

D. Desmopressin acts to increase water reabsorption in the kidneys, resulting in reduced urine output.A. Desmopressin primarily affects water reabsorption in the kidneys and does not typically have a direct effect on blood pressure. Blood pressure changes are not expected therapeutic outcomes of desmopressin therapy for diabetes insipidus.B. In diabetes insipidus, excessive urination can lead to dehydration and hypernatremia (high serum sodium levels). A therapeutic response to desmopressin would involve a decrease in serum sodium levels due to improved water retention and reduced urine output.C. Heart rate changes are not expected therapeutic outcomes of desmopressin therapy for diabetes insipidus.