A nurse is caring for a client who has hypertension and nephropathy due to type 2 diabetes mellitus. The nurse should expect to administer which of the following medications to slow the progression of the nephropathy?

A. "Sitagliptin": Sitagliptin is a DPP-4 inhibitor used to control blood sugar in type 2 diabetes. While it can help manage blood glucose levels, it does not directly target the progression of nephropathy. B. "Glipizide": Glipizide is a sulfonylurea used to lower blood glucose levels in type 2 diabetes. It is not effective in slowing the progression of diabetic nephropathy and is more focused on managing blood sugar. C. "Metoprolol": Metoprolol is a beta-blocker primarily used to control blood pressure and heart rate. While it can help with blood pressure, it does not specifically address nephropathy progression caused by diabetes. D. "Losartan": Losartan is an angiotensin II receptor blocker (ARB) commonly used to treat hypertension and protect kidney function, especially in clients with diabetic nephropathy. It can slow the progression of nephropathy by reducing proteinuria and controlling blood pressure.