A nurse is caring for a client who has posttraumatic stress disorder (PTSD) and is beginning psychopharmacology therapy. Which of the following medications is considered first-line treatment for symptoms of PTSD?

Choice A reason: Haloperidol is a typical antipsychotic used for schizophrenia and severe agitation, not for PTSD. It is not considered first-line treatment. Choice B reason: Sertraline, a selective serotonin reuptake inhibitor (SSRI), is first-line therapy for PTSD. SSRIs help reduce symptoms such as intrusive thoughts, hyperarousal, and avoidance behaviors by regulating serotonin levels. Choice C reason: Olanzapine is an atypical antipsychotic used for schizophrenia and bipolar disorder. It may be used adjunctively in PTSD but is not first-line. Choice D reason: Prazosin is used to treat nightmares associated with PTSD but is not considered first-line overall. It is often prescribed as an adjunct to SSRIs.