A nurse is caring for a client who has progressing chronic kidney disease (CKD). Which of the following laboratory results would the nurse expect to find in the client's electronic health record?

Choice A reason: In CKD, the GFR progressively decreases due to loss of nephron function. An increasing GFR would indicate improving kidney function, which is not expected in progressive CKD. Choice B reason: Increasing urine albumin is expected because CKD damages the glomerular filtration barrier, allowing albumin and other proteins to leak into the urine. Albuminuria is a hallmark of CKD progression and is used clinically to monitor disease severity. Choice C reason: Proteinuria does not decrease in CKD; instead, it increases as the disease worsens. Decreased proteinuria would suggest improvement or effective treatment, which is not consistent with progressive CKD. Choice D reason: Serum creatinine increases in CKD because the kidneys lose the ability to excrete it effectively. A decreasing creatinine level would indicate improved renal clearance, which is not expected in progressive disease.