A nurse is caring for a client who has tuberculosis and is taking rifampin. The client reports that her saliva has turned red-orange in color. Which of the following responses should the nurse make?

A. Rifampin commonly causes red-orange discoloration of body fluids, including saliva, urine, sweat, and tears. This is a harmless and expected effect of the medication and does not indicate toxicity. Clients should be reassured and educated about this side effect to reduce anxiety. B. Increasing fluid intake will not change the discoloration, as this effect is related to drug excretion, not dehydration. C. This expected side effect does not require discontinuation or change of therapy. Rifampin is a key medication in tuberculosis treatment and should be continued as prescribed unless serious adverse effects occur. D. Red-orange discoloration of body fluids is not a sign of toxicity. Signs of rifampin toxicity include hepatotoxicity (e.g., jaundice, dark urine, elevated liver enzymes), not colored secretions.