A nurse is caring for a client who is at 20 weeks of gestation and asks what could cause the infant to have a cleft lip. Which of the following responses should the nurse give?

A. Epstein-Barr virus (EBV) is not associated with cleft lip formation. B. Cleft lip is not caused by an autoimmune response. C. Advanced maternal age is associated with other congenital anomalies but not specifically with cleft lip. D. Cleft lip and palate often have a genetic component and can be influenced by environmental factors during early pregnancy.