A nurse is caring for a client who is experiencing opioid withdrawal. Which of the following manifestations should the nurse expect?

Choice A reason: Hypotension is not typically associated with opioid withdrawal. In fact, clients may experience elevated blood pressure and tachycardia due to autonomic hyperactivity during withdrawal. Choice B reason: Hyperreflexia is a common manifestation of opioid withdrawal. It reflects increased central nervous system excitability as the body reacts to the absence of the depressant effects of opioids. Other signs include piloerection, yawning, rhinorrhea, and muscle aches. Choice C reason: Respiratory depression is a hallmark of opioid intoxication, not withdrawal. During withdrawal, respiratory rate may increase due to anxiety and autonomic stimulation. Choice D reason: Slurred speech is more indicative of intoxication with central nervous system depressants, including opioids, but not withdrawal. Withdrawal symptoms are more activating than sedating.