A nurse is caring for a client who is receiving a blood transfusion at 125 ml/hr and develops a hemolytic reaction. Which of the following actions should the nurse perform?

A. Infuse 0.9% sodium chloride IV: The first action in a suspected hemolytic transfusion reaction is to stop the blood transfusion and maintain IV access with 0.9% sodium chloride. This helps prevent hypotension, supports renal perfusion, and allows for administration of fluids to reduce the risk of acute kidney injury from hemolyzed red blood cells. B. Administer an antipyretic: While fever may occur during a hemolytic reaction, administering an antipyretic is not the priority. Immediate supportive measures, including stopping the transfusion and maintaining IV access, take precedence to prevent severe complications. C. Decrease the infusion rate to 75 mL/hr: Slowing the transfusion is unsafe in the setting of a hemolytic reaction because the transfusion itself is causing a potentially life-threatening response. The infusion must be stopped entirely, not slowed. D. Place the client in a left lateral position: Positioning may be used in certain emergencies, such as to prevent aspiration or improve hemodynamics, but it is not a specific intervention for hemolytic transfusion reactions. The priority is to stop the transfusion and initiate fluid resuscitation.