A nurse is caring for a client who is receiving a unit of packed red blood cells. Fifteen minutes following the start of the transfusion, the nurse notes that the client is febrile, with chills and red-tinged urine. Which of the following transfusion reactions should the nurse suspect?

Choice A reason: Acute pain transfusion reaction is rare and typically presents with severe pain without hematuria. Choice B reason: Febrile reactions cause fever and chills but do not result in hemolysis or red-tinged urine. Choice C reason: Hemolytic transfusion reactions occur due to ABO incompatibility and present with fever, chills, and hemoglobinuria (red-tinged urine), indicating destruction of red blood cells. Choice D reason: Allergic reactions usually present with urticaria, itching, or anaphylaxis, not hematuria.