A nurse is caring for a client who is receiving morphine intravenously. Which of the following findings indicates the client is experiencing morphine toxicity?

Rationale: A. Hyperactive deep tendon reflexes are unrelated to opioid toxicity; they may occur in hypercalcemia or stimulant toxicity, not narcotic overdose. B. Fluid retention is not characteristic of morphine toxicity; opioids primarily depress the central nervous system and respiration. C. Prolonged QT interval is more often associated with medications such as methadone or certain antiarrhythmics, not morphine. D. Bradypnea (slow respiratory rate) is the hallmark of morphine toxicity due to central nervous system and respiratory depression. Other signs include sedation, pinpoint pupils, and decreased level of consciousness. The nurse should immediately stop the infusion, monitor vital signs, and prepare to administer naloxone, an opioid antagonist, as prescribed.