A nurse is caring for a client who is taking clozapine. For which of the following findings should the nurse withhold the medication?

A) The client has gained 1.4 kg (3 lb) in the past month: Weight gain can be a side effect of clozapine, but a 3-pound gain over the course of a month is not an immediate concern. The nurse should continue to monitor the client's weight, but this alone is not a reason to withhold clozapine. B) The client reports a sore throat: A sore throat could be a sign of a serious side effect of clozapine—agranulocytosis, a condition in which the body has a dangerously low white blood cell count, increasing the risk of infection. The nurse should withhold the medication and notify the healthcare provider immediately if the client reports a sore throat, as this is a potential early sign of agranulocytosis. A complete blood count (CBC) should be checked before continuing the medication. C) The client reports being constipated for 2 days: Constipation is a common side effect of clozapine due to its anticholinergic properties. While the nurse should address constipation and encourage interventions like increased fluid intake or stool softeners, it is not a reason to withhold clozapine unless the constipation becomes severe or leads to other complications like bowel obstruction. D) The client reports feeling dizzy when getting out of bed: Dizziness, particularly upon standing (orthostatic hypotension), is a common side effect of clozapine. The nurse should assess the severity of the dizziness and encourage the client to rise slowly from a sitting or lying position, but dizziness alone is not a reason to withhold the medication. However, if the dizziness is severe or persists, the nurse should notify the healthcare provider.