A nurse is caring for a client who is taking lisinopril. Which of the following outcomes indicates a therapeutic effect of the medication?

A. Prevention of bipolar manic episodes – Lisinopril is an ACE inhibitor used to treat hypertension and heart failure. It has no effect on mood disorders like bipolar disorder. B. Decreased blood pressure – Lisinopril works by blocking the conversion of angiotensin I to angiotensin II, leading to vasodilation and reduced blood pressure. This is the primary therapeutic effect of the medication. C. Improved sexual function – Lisinopril can actually cause sexual side effects such as decreased libido or erectile dysfunction in some clients. D. Increase of HDL cholesterol – Lisinopril does not affect cholesterol levels. HDL (good cholesterol) is usually managed with lifestyle changes and lipid-lowering medications like statins.