A nurse is caring for a client who is taking pseudoephedrine orally to treat allergic rhinitis. The nurse should assess for which of the following potential adverse effects of this medication?

Choice A rationale Pseudoephedrine is a sympathomimetic agent that primarily acts as a vasoconstrictor and bronchodilator. It does not directly affect kidney function to cause polyuria. In fact, due to its vasoconstrictive properties, it could theoretically decrease renal blood flow, although this is not a common or expected adverse effect leading to increased urine output. Choice B rationale Pseudoephedrine's primary mechanism of action involves stimulating alpha- and beta-adrenergic receptors. It does not have a known effect on appetite regulation; it is not typically associated with either increased or decreased appetite. Therefore, an increased appetite is not an expected adverse effect of this medication. Choice C rationale Pseudoephedrine is a sympathomimetic drug that stimulates adrenergic receptors, leading to effects similar to sympathetic nervous system activation. This stimulation typically results in tachycardia, not bradycardia. It increases heart rate and contractility, which can be problematic for individuals with pre-existing cardiovascular conditions. Choice D rationale As a sympathomimetic, pseudoephedrine causes vasoconstriction by stimulating alpha-1 adrenergic receptors in the arterioles. This widespread vasoconstriction leads to an increase in peripheral vascular resistance, which in turn can elevate blood pressure. Therefore, hypertension is a common and important adverse effect to monitor for, especially in individuals with pre-existing hypertension.