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    RN Comprehensive Predictor 2026 Proctored Exam V2

    A nurse is caring for a client who is to receive a transfusion of packed RBCs. Which of the following actions should the nurse take?

    Explanation & Rationale

    Blood transfusions must be primed with 0.9% sodium chloride (normal saline) because dextrose causes hemolysis of RBCs and lactated Ringer's may cause clotting. Blood warmers are used only in specific circumstances (massive transfusion, cold agglutinin disease) — routine warming for 1 hour is not appropriate. Blood transfusion tubing must contain an in-line filter to remove clots and cellular debris. A large-bore IV catheter (18-gauge or larger) is required for blood transfusions to prevent hemolysis.

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