A nurse is caring for a client who just received a dose of IV ampicillin. Which of the following client reactions requires priority intervention by the nurse?

A. A pulse rate of 110/min is elevated but not immediately life-threatening. B. Lower extremity angioedema indicates a severe allergic reaction, which can progress rapidly to airway compromise and requires immediate intervention. C. A blood pressure of 98/62 mmHg is mildly low but not the most urgent concern. D. Wheezing is serious, but angioedema involving the face or extremities may indicate impending airway obstruction, making it the priority.