A nurse is caring for a client who received a dose of IV morphine for pain. Which of the following vital signs indicates the client is having an adverse reaction to the medication?

A. Blood pressure 140/86 mm Hg: This blood pressure is slightly elevated but not indicative of an adverse reaction to morphine. Morphine more commonly causes hypotension rather than hypertension. B. Heart rate 65/min: A heart rate of 65/min is within normal limits for most adults and does not signal a concerning response to morphine. C. Temperature 37.5° C (99.5° F): This is a mild elevation within normal limits and is not associated with morphine administration. D. Respiratory rate 10/min: Morphine can depress the central nervous system, leading to respiratory depression. A respiratory rate of 10/min is below the normal range (12–20/min) and indicates an adverse reaction requiring immediate monitoring and intervention.