A nurse is caring for a client who received alteplase 12 hr ago following a thrombotic stroke. The nurse should monitor the client for which of the following adverse effects?

A. This is the most critical adverse effect associated with alteplase administration. Alteplase works by promoting fibrinolysis (breaking down blood clots), which can increase the risk of bleeding, including intracranial hemorrhage.B. Steatorrhea refers to fatty stools and is not typically associated with alteplase administration. This side effect is more commonly seen with conditions affecting fat absorption or certain medications, not thrombolytic therapy.C. Polycythemia is an increase in the number of red blood cells and is not a typical adverse effect of alteplase. Alteplase does not affect red blood cell production or cause polycythemia.D. Laryngospasm is a sudden spasm of the vocal cords that can cause difficulty breathing or choking and is not directly associated with alteplase use. This adverse effect can occur due to various causes, such as irritation, allergic reactions, or certain medical conditions, but not from alteplase administration.