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    Ati Rn pharmacology proctored exam 2023

    A nurse is caring for a client who received succinylcholine IV bolus during an abdominal surgery. The client develops malignant hyperthermia. The nurse should administer which of the following medications?

    Explanation & Rationale

    A. Naloxone: Naloxone is an opioid antagonist used to reverse opioid overdose or respiratory depression. It has no effect on the pathophysiology of malignant hyperthermia. B. Acetylcysteine: Acetylcysteine is the antidote for acetaminophen toxicity and works by replenishing glutathione. It does not treat malignant hyperthermia. C. Baclofen: Baclofen is a muscle relaxant used to manage spasticity in conditions such as multiple sclerosis. It is not indicated for malignant hyperthermia. D. Dantrolene: Dantrolene is the drug of choice for malignant hyperthermia. It acts by reducing calcium release from the sarcoplasmic reticulum in skeletal muscle, which decreases muscle rigidity, hypermetabolism, and prevents life-threatening hyperthermia.

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